Memory Loss and Alzheimer's Resources

By Dr. Fred Raleigh
Plus Magazine
Date: 12/04


Question.
My dad, who is in his late 70's, seems to be having more and more problems with his memory. One part of me wants to just think it is part of the aging process; and yet, another part of me worries that he may have dementia or Alzheimer's Disease.

My other siblings and I have talked about some of the agents we read about regarding helping those out with Alzheimer's. Yet, we seem to get into fights and cannot resolve the main issue as to whether dad should be receiving one of these medications or not.

Can you provide any help in this family matter?

ER Paso Robles, CA


Answer.

Like so many other adult children you and your siblings are wrestling with a growing problem in our country, namely the aging of our parents, the normal loss of memory associated with aging and the possible development of dementia of which Alzheimer's is one type.

First, lets talk about a recent VHS/DVD that I came across that deals with the subject of Alzheimer's and is geared for family members and care providers. What I liked the most about this video/DVD is that the makers of this program want you to know that there is hope at any stage of the disorder and things are not hopeless

The VHS/DVD is called: "Alzheimer's Disease: A New Hope Through Understanding." The program is ideal for those wanting to learn more, nursing homes or residential care facilities to have in their help libraries or for small groups of people to share.

The short and very informative presentation is well organized and focuses on the very issue you and your other family members may currently be wrestling with.


What I found interesting about this particular program is that is goes into great detail to lay out a proper understanding about the early phases of the disease and what progress has been made over the last decade with regards to the management of this problem.

The program provides concise and helpful information that is easy to understand and allows for the viewer to see just where their loved one may be in the process of aging and possible dementia and Alzheimer's. In addition, the role of various healthcare professionals is explained as well as what tests, medications and other supportive tools are currently available to help the person with the problem and the loved ones providing care.

I found and so may you, that the way the behavioral aspects of the disease are presented is both refreshing and enlightening. It is easy for people to see the subtle changes in personalities that can take place in people who develop or may be developing dementia or Alzheimer's.

At the end of the program there is a nice list of support organizations that one can contact to receive more information related to caring for and managing the disorder.

Unfortunately, unlike movie DVD's, you cannot return to certain sections on the DVD should you have to stop the DVD to carry on with other business or find that you did not have time to write down the information provided at the end of the program. Yet, the DVD is not long, the cost is reasonable and there is no commercialization at all in the video....a rare treat in today's commercially oriented world.

Interestingly if you happen to be a nurse reading this review you can obtain 1.5 CE hours along with a work book. The CE is on either in VHS or DVD format and the workbook is on a CD-ROM.

You can obtain a VHS or DVD copy of this fine program by contacting Models of Hope Media at 866-823-8851.

There currently is an introductory price for readers of this column of $24.95 or $29.95 if you also want CE credit. Or you can order by mailing your request to 13240 Clairepoint Way, Oakland, CA 94619. There is a modest shipping and handling fee of $6.95 along with obligatory taxes.

Next, if you find you cannot afford the VHS/DVD program I'd like to share with you some excellent resources that are available locally and on-line if you have a computer.

In a recent article that appeared in The Wall Street Journal (September 2004) the following web sites were briefly discussed. You may find some useful and informative information to help aid your family's decision process. You might want to start at the local association of the National Alzheimer's Association. More can be learned at the national associations web site www.alz.org At the site you want to click on, "About Alzheimer's" to get more information. The site also will direct you to local support chapters. Next, we have the Alzheimer's Disease Education and Referral Center located at www.alzheimers.org

This site is provided by the National Institute on Aging and one of the most useful bits of information provided is the clinical-trials database link that allows you to get information about medications used for Alzheimer's.

Unfortunately, the studies reported are mostly government funded studies and there is little information about studies that have been funded by the actual drug manufacturers.

There is also the Alzheimer's Research Forum found at www.alzforum.org A comprehensive site designed for both scientists and lay people. This site can be thick at times. Yet, it is good for those that want to dig deep into the problem. And finally, there is the Family Caregiver Alliance that can be accessed by typing www.caregiver.org These folks provide many useful fact sheets and information on "Therapeutic Lying." A very interesting concept for dealing with those of us who develop dementia or Alzheimer's.

Next, I'd like to share with you information about the medications that we currently have at our disposal to aid those suffering from dementia. What is important to remember is that these drugs seem to retard the progress of the disease process and in some cases slow development down significantly. Do these agents actually stop memory loss? No! Do these agents help to improve the quality of life for the patient and/or the primary care providers? Yes!

There is a growing body of medical evidence supporting the use of these products for the long haul. Yes, these products can be expensive. It also appears that these products not only help with memory loss but they may also provide some behavioral help for close to half of the people with Alzheimer's who experience anxiety and aggression with the disease.

There is also information that shows us that in many, but not all cases, memory decline has remained fairly stable for 4-6 years. I think the secret here is that medication use was started earlier on in the course of the disease vs. later on.

Currently there are four agents approved for the management of memory loss in dementia and/or Alzheimer's. The first three, Reminyl by Johnson and Johnson, Aricept by Pfizer, Exelon by Novartis, all work to help keep the levels of natural brain chemicals believed to be involved in memory functioning stable for longer periods of time. The fourth agent, Namendia by Merz, a German company, has a totally different mechanism of action. This product retards the brain's chemical believed to be responsible for brain cell damage and death.

More information about any of these products can be gained by simply typing into your web browser the following: www.reminly.com or www.aricept.com or www.exelon.com or finally, www.namendia.com Once you are at these sites you will also be exposed to a wealth of information about the care and management of Alzheimer's.

On a closing and personal note I would like to let readers know that for more than 20 years I have served as a consultant pharmacist in skilled nursing facilities. I have seen first hand the problems families experience when a loved one develops dementia and/or Alzheimer's Disease. My experience tells me that in many cases the family waited far to long before seeking treatment and the quality of life of their loved one has suffered tremendously.

Also, I have seen family members asking to have the Alzheimer's agents stopped because they did not want to prolong their loved one's life. In many cases, these abrupt discontinuations have led to serious episodes of aggression in patients as all of a sudden their memory loss and subsequent confusion are now magnified.

The use of medication's designed to retard memory loss and possible brain damage due to Alzheimer's are not known to increase one's life span. These agents are designed and used to assist an individual's cognitive thought processes so that during their waning years they have a higher quality life.

In closing you should know that there are memory tests that doctor's use to evaluate memory. One simple test you can do at home, providing your dad will want to cooperate, is to do a word memory test. You can give him a list of 10 short words to learn and tell him you are going to ask him to recall this list in 5 minutes and 30 minutes. The normal for people in their seventies and without dementia, is to be able to recall approximately 7 words.

I would encourage you and your other family members to learn all you can about the problem of memory loss associated with aging and the possibility of this memory loss being related dementia or Alzheimer's. You should have many places to explore after reading this response.

Plus 12-04


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